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Trace · PDE5 trace
Last reviewed · 9 min read · Updated
Orbit card
| Onset | Can be early if fasting |
|---|---|
| Duration | Hours, not a tadalafil tail |
| Food | High-fat cuts and delays peak |
| Alcohol | Hypotension stack |
Levitra marketing leaned on speed. Pharmacology is a Tmax that can sit early when the stomach is empty, then stretch when a high-fat meal cuts Cmax and delays the peak - on the order of an 18-50% Cmax drop in label food studies, depending on the meal design. People who swallow 5 mg with a late lamb dinner decide the molecule is 'slow like the others'. They then take a second tablet. That is the onset pairing this page exists to stop.
This site's lock is 2.5-5 mg, not the 10-20 mg tourist default. Those lower strengths are exactly where the label already parks patients on CYP3A4 inhibitors and on stable alpha-blockers. Treating 5 mg as a timid starter while a booster is on board misses the point of 2.5.
Nitrates and riociguat close vardenafil the same way they close the class. The faster peak does not shorten a nitrate emergency into a casual evening spray. If chest pain happens, say vardenafil and the clock. Do not bargain with 'it was only 2.5'.
Class IA and III antiarrhythmics plus congenital long QT are vardenafil-specific avoid rows. They get their own QT trace. This page keeps the clock: food, CYP, alpha-blockers, alcohol, and the urge to restack because the first 40 minutes felt empty.
Full tables: vardenafil orbit.
Onset pairing chip
Vardenafil's duration is closer to sildenafil than to tadalafil. People still must not invent a two-hour nitrate clearance because the onset felt brisk.
If a patient is switching from Cialis 20 mg, leftover tadalafil can still occupy Saturday while they try 'fast' Levitra 5 mg. That is class stacking, not an onset upgrade.
Sildenafil 25-100 the same night as vardenafil 2.5-5 is the same stack. Pick one short-acting INN.
Combo 100/20 strips add tadalafil's tail under a vardenafil plan if someone 'supplements' - refuse that hybrid.
Ritonavir raised vardenafil exposure sharply and stretched half-life toward a day. Labeled answer: 2.5 mg, not again for 72 hours. A traveler who takes 5 mg Friday and 5 mg Monday while boosted is still guessing.
Indinavir, saquinavir, atazanavir, ketoconazole 400 mg daily, itraconazole 400 mg daily, clarithromycin: no more than 2.5 mg in 24 hours. Ketoconazole 200 mg, itraconazole 200 mg, erythromycin: no more than 5 mg in 24 hours. Those numbers are why 2.5-5 is the lock, not a shy range.
Grapefruit is a quieter CYP3A4 nudge. With a 'fast' drug, a later-than-adverted peak plus higher exposure is how people describe a 'weird strong' evening after brunch.
Do not climb to 10 or 20 mg to beat an inhibitor. Climbing into a blocked enzyme is the opposite of onset control.
| Partner | Onset implication |
|---|---|
| High-fat meal | Peak later, Cmax down - wait, do not redose |
| Ritonavir | 2.5 mg, 72 h gap |
| Strong azole / certain PIs | 2.5 mg / 24 h |
| Erythromycin / keto 200 | 5 mg / 24 h ceiling |
A rapid rise on an empty stomach plus alcohol is a standing-dizziness design. The speed people wanted becomes the faint they get.
Harbour evenings that pair a 5 mg swallow with spirits and a soak should treat vardenafil like any PDE5: heat and ethanol add to the drop. Speed does not protect you.
Do not take 2.5 mg 'because it is small' and then drink as if no PDE5 were present. Milligrams do not waive the stack.
Antihypertensives at supper plus 5 mg at 19:30 can align two nadirs. Write both times.
Tourist strips labeled 20 mg sell speed-plus-strength. They do not digest fat faster. They do not cancel ritonavir's 2.5 mg every 72 hours. They do not make amiodarone safe.
A first-ever vardenafil as 20 mg because 5 felt shy is how orthostasis and headache get blamed on the brand. This site's lock is 2.5-5 mg for a reason: that is where the pairing table already lives.
If a pharmacist in Reykjavik cannot find vardenafil and a milligram on the foil, the onset conversation is closed. Logo lightning bolts are not Tmax.
Switching from leftover tadalafil 20 mg to export vardenafil 20 mg the next morning is still class stacking. Fast is not a washout.
Keep 2.5-5 questions on the parent vardenafil orbit until a clinician moves the strength. Export 20 is not self-serve onset therapy.
A tourist who bought 20 mg because the airport shop had no 5 mg still owns the CYP table. If ritonavir or ketoconazole 400 mg is on the list, that 20 mg strip is the wrong strength even if the onset ad was printed on the box. Leave it sealed until clinic says otherwise.
Psychogenic delay, SSRI flattening, and no stimulation will make any Tmax look like failure. A second 5 mg will not fix an empty cue.
QT partners can close vardenafil regardless of how attractive the onset is. If amiodarone is on the list, stop shopping for speed and open the QT trace.
Hepatic impairment has its own vardenafil caps on the parent orbit. Onset claims do not override liver rows.
Export 20 mg taken as a first tablet because 'Levitra is weak at 5' ignores this lock and the inhibitor table. Bring 2.5-5 questions to clinic first.
High-fat meals reduce vardenafil Cmax and push Tmax later. The 'fast' reputation dies on the same Saturday sildenafil dies - a heavy plate and a 40-minute expectation.
ODT vardenafil (Staxyn-type) has its own food rules on some labels and is not a loophole to eat a burger and keep a film-coated 5 mg plan. If the pack is ODT, the orbit's formulation row wins over this film-coated onset note.
A delayed 5 mg peak plus a impatient second 5 mg is 10 mg without a single-peak plan. Frequency remains one tablet per day unless a clinician wrote otherwise.
If every late dinner fails and every late-morning fasting 5 mg works, you have a meal pairing, not proof you need 20 mg from an export strip.
Write swallow clock, plate fat as light or heavy, minutes until any effect, standing symptoms, and other medicines that day. Four columns beat a vibe that Levitra is fast or dead.
If three heavy-plate nights show a late flat peak and one fasting 5 mg night shows an earlier rise, you have a meal pairing. Bring that week to clinic before anyone writes 20 mg.
If every night is fasting 5 mg and nothing happens, the diary still matters: it proves food is not the thief. Then the work-up or the QT list or a skyline switch can start.
Occupational drivers should add alertness after the peak. A fast drop in blood pressure is a lane problem, not a bedroom score.
Do not add a second 2.5 mg row the same night 'to complete the diary'. The diary is observational. Redose is an experiment the label did not ask for.
Labeled vardenafil start on stable alpha-blockade is 5 mg. The early peak that marketing likes is the same hour orthostasis likes.
Standing at 40 minutes after a first 5 mg on tamsulosin is a blood-pressure moment. Sitting through the peak is counseling, not cowardice.
2.5 mg exists for inhibitor caps and for clinicians who want an even lower first look. It is not 'half a weekend'. It is a pairing strength.
Starting the alpha-blocker and vardenafil the same week is the sequencing error shared with tadalafil and sildenafil. Stabilize one.
List CYP3A4 drugs, alpha-blockers, QT drugs, meal fat, and last other PDE5 before you trust a 30-minute story. Parent: vardenafil orbit.
If the list includes quinidine, procainamide, sotalol, or amiodarone, leave this onset page for the QT trace. Prescribers set the tablet. This desk charts thieves of the peak.
Checked against the current label and reviewed by Dr. Ingrid Bergsson. See Lift, Chart, Peer-pass, Publish.
Levitra 2.5-5 onset thread - educational only. Collapse: 112.
Arndis L., Grandi dinner 5 mg with lamb at 20:00. Nothing at 20:40. Another 2.5?
No. High-fat meals delay and flatten vardenafil's peak. 20:40 can still be the climb. A second tablet the same night is an unplanned 7.5 mg and a stacked peak when the first arrives. Wait. Next evening: 5 mg off the heavy plate if the prescriber still wants 5. If a booster is on your list, 5 mg may already be too high - check the 2.5 caps.
Petur A., sinus Erythromycin. Stay on 5 mg Levitra I already use?
Erythromycin's labeled vardenafil ceiling is 5 mg in 24 hours - so 5 mg may still be the cap, not a climb. Do not add a second 5. If you were heading toward 10 mg habits, stop. New faintness on the macrolide plus 5 mg is a same-day message, not a food problem.
Margret I., first 5 mg Tamsulosin stable. First Levitra 5 mg - spots when I stood at 35 minutes.
That hour is the peak people wanted and the orthostatic window the alpha-blocker pairing predicts. Sit, log pressures, do not redose. Tell clinic before any 10 mg fantasy. 2.5 mg may be their next look. Do not stop tamsulosin alone.
Disa R., cardiology On amiodarone. I only want the fast 5 mg, not a QT lecture.
Hannes Y., boosted Ritonavir. Can I use 5 mg because I want the fast peak?
Ritonavir's labeled vardenafil cap is 2.5 mg and not another dose for 72 hours. Speed is irrelevant against a half-life stretched toward a day. 5 mg is the wrong strength here. Ask clinic for the 2.5 plan, not a 'small 5'.
Asta D., oral azole Ketoconazole 400 mg daily. Is 5 mg still the low Levitra?
At ketoconazole 400 mg daily the labeled vardenafil cap is 2.5 mg in 24 hours, not 5. 5 mg is already above that row. Contact the prescriber before any further tablet. Onset stories do not outrank the azole table.
Hildur W., empty stomach 2.5 mg fasting plus three drinks - felt it fast, then nearly fainted.
Empty-stomach peak plus alcohol is a designed drop. 2.5 mg does not waive the stack. Sit, skip further PDE5 that night. If collapse or chest pain, 112 and name vardenafil. Next time the drinks are part of the onset plan, not a surprise after the stopwatch.
Andri F., weekend leftover Cialis 20 mg Friday. Levitra 5 mg Saturday for speed?
Friday tadalafil is still a Saturday pairing. Adding vardenafil is class stacking, not an onset upgrade. Wait the tadalafil 24-hour frequency rule and the longer nitrate tail before any short-acting switch. Prescriber clears leftover tadalafil. Do not chase fast on top of a 17-hour half-life.
Oddny K., two short agents Sildenafil 50 at 18:00 failed. Levitra 5 at 21:00 for a faster second try?
Two short-acting PDE5 inhibitors in one evening is still a stack. 18:00 to 21:00 is inside sildenafil's day. Wait the 24-hour sildenafil window or let clinic switch you cleanly to one INN. Fast onset is not a rescue protocol.
Arni G., liver note Moderate hepatic impairment. Friend says 5 mg is tiny so it must be fine.
Hepatic caps live on the parent orbit and can sit at 5 mg or below depending on Child-Pugh. Tiny is not a clearance assay. Bring the liver letter to clinic before any 5 mg habit. Do not use export 20 mg to compensate for a small labeled strength.
Desk seal Onset-visit packet?
Exact 2.5 or 5 mg, swallow clock, meal fat, CYP3A4 list with doses (ritonavir, azoles, macrolides), alpha-blocker name, any QT drug, last other PDE5, and whether a fasting attempt ever worked. Parent: vardenafil orbit. If antiarrhythmics appear, go to the QT trace first.